Twilight Boutique, 11025 Prosepct Road, was broken into eary Monday morning -- for the second time this week and the fourth time in a year.
A report said an alarm went off shortly before 5 a.m. Police arrived to find the back door pried open.
On Aug. 28, someone smashed the front glass of the business and took items from inside.
The leafy material in the packets is treated with chemicals that produce a marijuana-like high when smoked, authorities say.
Also available there are the so-called "bath salts," which also provide a high when snorted.
Someone also threw a brick through the front window Nov. 28, running in and grabbing merchandise and then fleeing.
On Dec. 11, someone -- police believe it may have been the same culprits, returning two weeks later -- again threw a concrete block through the door.
That time, audible alarms went off, sending the intruders running.